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KMID : 0355420020260020251
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Journal of Korean Academy of Oral Health
2002 Volume.26 No. 2 p.251 ~ p.257
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A study on the halitosis reduction by dentifrice containing triclosan, GFSE, eucalyptus oil and flavonoid
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Abstract
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The aim of this study was to assess the effect of the dentifrice containing 0.2% triclosan, 0.1% Grapefruit seed extract(GFSE), 0.19% Eucalyptus oil and 0.25% flavonoid on malodor. The negative control contained no antibacterial agents. In vivo study, the case control, double-blind and crossover design was used, and 40 healthy subjects aged from 20 to 30 participated. On baseline, subjects received the same toothbrushes and were requested to clean their teeth three times daily. Halitosis level was determined by halimeter. Halitosis levels of all subjects were determined at baseline, 1 hour after mouthrinsing with slurry of dentfrice and distiled water after 1week and 3 weeks. After 6weeks of refreshing period, experimental and control group were changed each other, and halitosis levels of all subjects were determined again. 1 hour after mouthrinsing with slurry of dentfrice and distiled water mean halitosis level was not different between experimental and control group(p) 0.05). But, mean halitosis level of experimental group was lower than control after 1 week and 3weeks(p (0.05). As a result, it was suggested that the dentifrice which contained 0.2% triclosan, 0.1% Grapefruit seed extract(GFSE), 0.19% Eucalyptus oil and 0.25% flavonoid be effective on halitosis.
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KEYWORD
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